面向患者就诊准备的 AI 随机对照研究
A prospective randomized study of patient-centered AI for clinical visit preparation
研究团队基于 LLM 设计就诊准备智能体，在 Google Health app 中开展前瞻性随机研究，802 名美国成年人共进行 866 次健康对话。临床评审显示该智能体完整准备率达 67.2%，高于对照组的 50.6%，与患者健康背景的契合度为 98.9% 对 90.4%；患者自评的就诊准备度、提问信心和整体满意度也分别高出 16.8%、14.3% 和 12.0%。
Authors:Xincheng Tan, Matthew Thompson, Xiang Ji, Angelica Willis, Will Vaughan, Roma Ruparel, Michael A. Sanchez, Sean Chang, Joseph Xu, Bhavna Daryani, Preeti Singh, Pinal Bavishi, Kejia Chen, Fan Zhang, Priya Gupta, Ernest Lim, Christina Chen, Bob Lou, Dimitrios Antos, Zach Wasson, Ray Luo, Fadi Yousif, Florence Thng, Mark Malhotra, Joseph Breda, Daniel McDuff, Kavi Goel, Katherine Chou, Dale R. Webster, Avinatan Hassidim, Yossi Matias, Po-Hsuan Cameron Chen, Yun Liu, Mike Schaekermann, Quang Duong, Jackie M. Barr
Abstract:Patients often arrive at brief, time-constrained clinical visits unsure of what to expect or ask, and millions of adults now turn to general-purpose AI chatbots to prepare beforehand. Yet whether conversational AI improves visit readiness remains unclear. We designed a large language model (LLM)-based visit preparation agent to guide patients before an appointment by gathering clinical context, setting visit expectations, providing relevant health information, building a prioritized list of questions for their clinician, and generating a summary. In a prospective consented randomized study in the Google Health app, 802 U.S. adults held 866 health-related conversations with the visit preparation agent (standard or concise variant) or a minimally prompted control chatbot built on the same LLM. The visit preparation agent significantly outperformed the control across blinded clinician evaluations and patient self-reports. In clinician reviews of completed sessions (n = 272), the agent achieved a 16.6% higher rate of comprehensive preparation (67.2% vs. 50.6%; P < 0.05) and an 8.5% higher rate of alignment with patients' health context (98.9% vs. 90.4%; P < 0.01), while maintaining high medical safety and appropriateness across all study arms. Patient post-surveys (n = 460) showed 16.8% higher visit preparedness (73.8% vs. 57.0%; P < 0.01), 14.3% higher confidence in knowing what to ask (81.4% vs. 67.1%; P < 0.01), and 12.0% higher overall satisfaction (74.0% vs. 62.0%; P < 0.05). Clinician and participant metrics were not significantly correlated, indicating that expert review and patient self-assessment capture complementary dimensions of patient-facing AI. These findings suggest that LLM chatbots can safely help patients prepare for clinical visits, with greater benefit when following a structured workflow, and motivate future studies on in-visit communication and clinical outcomes.
| Comments: | 50 pages (16 main text, 34 appendix), 6 figures |
| Subjects: | Human-Computer Interaction (cs.HC); Computation and Language (cs.CL); Machine Learning (cs.LG) |
| Cite as: | arXiv:2610.41437 [cs.HC] |
| (or arXiv:2610.41437v1 [cs.HC] for this version) | |
| https://doi.org/10.48550/arXiv.2610.41437 arXiv-issued DOI via DataCite (pending registration) |
Submission history
From: Xincheng (Cara) Tan [view email]
[v1]
Fri, 30 Oct 2026 08:39:59 UTC (2,916 KB)
来源：arXiv cs.CL · arxiv.org